ABSTRACT
La leptospirosis es una enfermedad infecciosa aguda, poco frecuente, que se adquiere por contacto de aguas servidas y contaminadas por orina de ratas infectadas. Clínicamente se caracteriza por un síndrome febril agudo bimodal con compromiso hepático, renal y meníngeo asociada ocasionalmente a manifestaciones purpúricas y que cursa con leucocitosis y neutrofilia. El diagnóstico clínico se confirma bacteriológica y serológicamente. El tratamiento de elección es la penicilina en dosis diaria de 5 a 10 millones, administrada precozmente, lo que implica un alto índice de sospecha clínica.
Subject(s)
Humans , Weil Disease/diagnosis , Weil Disease/therapySubject(s)
Humans , Male , Middle Aged , Weil Disease/diagnosis , Weil Disease/prevention & control , Weil Disease/therapy , Chile , LeptospirosisABSTRACT
Adult male after swimming in flood water in an urban area presented icterohaemorrhagic leptospirosis and septicemic salmonellosis. Severe clinical signs were characterized by fever, septicemia, jaundice, vomiting, haemorrhagic diarrhea and acute kidney failure. Peritoneal dialysis and treatment with penicillin and chloramphenicol were applied. Diagnosis was made on clinical, epidemiological and laboratorial basis. There was anticorpic seroconversion specific for L icterochaemorrhagiae. Hemocultures were positive for Salmonella with antigenica structure 4,5,12:i:-, a possible monophasic variant of S. typhimurium, 05 + (4,5,12:i:1,2). The patient survived. Attention is called to the cumulative risks for diseases acquired on exposure on exposure to floods, such as this double occurrence of diseases, both of animal origin. In view of clinical signs of comparable pathogenic and epidemic expression, investigation should be directed towards laboratorial tests for concurrent diseases